ABSTRACT
Introduction: Frontline nurses caring for COVID-19 patients are easy to get viral infections because they are often exposed to infected patients. As the virus continues to spread, frontline nurses were faced with situations that can affect psychological readiness. This study was to explore the psychological aspects of frontline nurses caring for COVID-19 patients. Methods: In-depth interviews were conducted with 16 frontline nurses providing care for COVID-19 patients at a referral hospital in Surabaya from August to October 2020. Interviews were conducted face-to-face or by telephone and analyzed with Colaizzi. Results: The results show that there are 3 main psychological themes for frontline nurses who treat COVID-19 patients. First, the emotions that appear in the begining stages consist of fear and anxiety about being infected and anxiety about the poor of knowledge about the disease and lack of information regarding the patient's condition are challenges that must be solved in the long term. Second, positive emotions appear progressively after negative emotions along with the ability to get used to the existing situation. Third, we find that nurses being able to take lessons and important values by increasing alertness, always being grateful, and thinking positively. Conclusion: We conclude that during the pandemic, the positive and negative emotions of frontline nurses are indirectly internalized into one. Frontline nurses are able to take lessons and interpret their primary roles Along with good emotional control, frontline nurses are able to take lessons and important values from the pandemic events they are facing. © 2022 UPM Press. All rights reserved.
ABSTRACT
Background: The prevalence of COVID-19 cases in Indonesia as of June 9, 2020, has been confirmed 32.076 positive cases, with 1.923 death cases. The total number of deaths reached 92,941 cases. There has been a recent update on stem cell-based biological, medical therapy as an optional treatment to handling COVID-19 due to its potential viability besides using the prevalent conventional chemical drug therapy. Methods: In this study, in vitro research was conducted to determine the potential of hematopoietic stem cells (HSCs) and natural killer cells (NK cells) against SARS-CoV-2 viruses, which virus isolates were collected in Indonesia. The SARS-CoV-2 virus was planted in rat kidney cells and Vero cells. The cells that had been planted with the virus were given HSCs and NK cells, followed by being evaluated at intervals of 24, 48, and 72 hours. The evaluation was done by collecting cells and supernatant from the cell plate and then determining the viral load using a Polymerase Chain Reaction (PCR) machine. Results: The results showed that the addition of HSCs and NK on cells that had been infected by SARS-CoV-2 resulted in a decrease in viral load within 24 to 72 hours in all variations of Multiples of Infection (MoI) values. Conclusions: The administration of HSCs and NK cells has the potential to eliminate the SARS-CoV-2 virus. Although this study is only an in vitro study, it could be the basis for the development of alternative stem cell-based therapies to tackle COVID-19 cases. © 2020 EManuscript Technologies. All rights reserved.